Chain and conformation stability of solid-state DNA: implications for room temperature storage

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Nucleic Acids Research Volume 38, Issue 5
Bonnet J., Colotte M., Coudy D., Couallier V., Portier J., Morin B., Tuffet S.
https://academic.oup.com/nar/article/38/5/1531/3112491
There is currently wide interest in room temperature storage of dehydrated DNA. However, there is insufficient knowledge about its chemical and structural stability. Here, we show that solid-state DNA degradation is greatly affected by atmospheric water …Read More

Thèse de doctorat sur la stabilité de l'ADN à l'état secPhD Thesis on the stability of dry state DNA

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Colotte M. Stabilité chimique et conformationnelle de l’ADN à l’état sec et à température ambiante Thèse N°1535 Université de Bordeaux 2, 2008, présidée par M. Jean Weissenbach, directeur du Génoscope.
Présentée et soutenue à huis clos.Colotte M. Stabilité chimique et conformationnelle de l’ADN à l’état sec et à température ambiante Thèse N°1535 Université de Bordeaux 2, …Read More

Simultaneous assessment of average fragment size and amount in minute samples of degraded DNA

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There is currently no method allowing routine characterization of minute amounts of degraded DNA samples such as those encountered in forensic science, archived tissues, ancient DNA, extracellular or stool DNA or processed food. Here, we describe and directly validate such a method based, on one hand, on a generalized DNA random fragmentation model and on …Read More

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